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Development and Use of the Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy Axicabtagene Ciloleucel in Large B-Cell Lymphoma: A Review

IMPORTANCE: Axicabtagene ciloleucel, an anti-CD19-CD28-CD3ζ chimeric antigen receptor T-cell therapy, was the first US Food and Drug Administration–approved, genetically engineered T-cell therapy for adults with relapsed or refractory large B-cell lymphoma (LBCL) after 2 or more lines of systemic th...

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Detalhes bibliográficos
Publicado no:JAMA Oncol
Main Authors: Locke, Frederick L., Go, William Y., Neelapu, Sattva S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7859915/
https://ncbi.nlm.nih.gov/pubmed/31697310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2019.3869
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