BCL-XL inhibition by BH3-mimetic drugs induces apoptosis in models of Epstein-Barr virus–associated T/NK-cell lymphoma

Epstein-Barr virus (EBV)–associated T- and natural killer (NK)–cell malignancies, such as extranodal NK-/T-cell lymphoma (ENKTL), exhibit high chemoresistance and, accordingly, such patients have a poor prognosis. The rare nature of such cancers and nonmalignant T/NK lymphoproliferative disorders, s...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Sejic, Nenad, George, Lindsay C., Tierney, Rosemary J., Chang, Catherine, Kondrashova, Olga, MacKinnon, Ruth N., Lan, Ping, Bell, Andrew I., Lessene, Guillaume, Long, Heather M., Strasser, Andreas, Shannon-Lowe, Claire, Kelly, Gemma L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556124/
https://ncbi.nlm.nih.gov/pubmed/33017468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002446
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