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3D Bone Morphology Alters Gene Expression, Motility, and Drug Responses in Bone Metastatic Tumor Cells

Patients with advanced skeletal metastases arising from primary cancers including breast, lung, and prostate suffer from extreme pain, bone loss, and frequent fractures. While the importance of interactions between bone and tumors is well-established, our understanding of complex cell–cell and cell–...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Dadwal, Ushashi C., Merkel, Alyssa R., Page, Jonathan M., Kwakwa, Kristin A., Kessler, Michael, Rhoades, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555977/
https://ncbi.nlm.nih.gov/pubmed/32967150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186913
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