Ligation-Mediated Polymerase Chain Reaction Detection of 8-Oxo-7,8-Dihydro-2′-Deoxyguanosine and 5-Hydroxycytosine at the Codon 176 of the p53 Gene of Hepatitis C-Associated Hepatocellular Carcinoma Patients

Molecular mechanisms underlying Hepatitis C virus (HCV)-associated hepatocellular carcinoma (HCC) pathogenesis are still unclear. Therefore, we analyzed the levels of 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) and other oxidative lesions at codon 176 of the p53 gene, as well as the generation of...

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Publicado no:Int J Mol Sci
Main Authors: Galli, Andrea, Munnia, Armelle, Cellai, Filippo, Tarocchi, Mirko, Ceni, Elisabetta, van Schooten, Frederik Jan, Godschalk, Roger, Giese, Roger W., Peluso, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555735/
https://ncbi.nlm.nih.gov/pubmed/32942546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186753
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