8-Oxo-7,8-dihydro-2′-deoxyguanosine and other lesions along the coding strand of the exon 5 of the tumour suppressor gene P53 in a breast cancer case-control study

The next-generation sequencing studies of breast cancer have reported that the tumour suppressor P53 (TP53) gene is mutated in more than 40% of the tumours. We studied the levels of oxidative lesions, including 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG), along the coding strand of the exon 5 in b...

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Publicado en:DNA Res
Autores principales: Brancato, Beniamino, Munnia, Armelle, Cellai, Filippo, Ceni, Elisabetta, Mello, Tommaso, Bianchi, Simonetta, Catarzi, Sandra, Risso, Gabriella G., Galli, Andrea, Peluso, Marco E.M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991831/
https://ncbi.nlm.nih.gov/pubmed/27260513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/dnares/dsw018
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