Anticancer Imidazoacridinone C-1311 is Effective in Androgen-Dependent and Androgen-Independent Prostate Cancer Cells

The androgen receptor (AR) plays a critical role in prostate cancer (PCa) development and metastasis. Thus, blocking AR activity and its downstream signaling constitutes a major strategy for PCa treatment. Here, we report on the potent anti-PCa activity of a small-molecule imidazoacridinone, C-1311....

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Niemira, Magdalena, Borowa-Mazgaj, Barbara, Bader, Samuel B., Moszyńska, Adrianna, Ratajewski, Marcin, Karaś, Kaja, Kwaśniewski, Mirosław, Krętowski, Adam, Mazerska, Zofia, Hammond, Ester M., Skwarska, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555468/
https://ncbi.nlm.nih.gov/pubmed/32825120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8090292
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