Anticancer Imidazoacridinone C-1311 is Effective in Androgen-Dependent and Androgen-Independent Prostate Cancer Cells

The androgen receptor (AR) plays a critical role in prostate cancer (PCa) development and metastasis. Thus, blocking AR activity and its downstream signaling constitutes a major strategy for PCa treatment. Here, we report on the potent anti-PCa activity of a small-molecule imidazoacridinone, C-1311....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biomedicines
Prif Awduron: Niemira, Magdalena, Borowa-Mazgaj, Barbara, Bader, Samuel B., Moszyńska, Adrianna, Ratajewski, Marcin, Karaś, Kaja, Kwaśniewski, Mirosław, Krętowski, Adam, Mazerska, Zofia, Hammond, Ester M., Skwarska, Anna
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555468/
https://ncbi.nlm.nih.gov/pubmed/32825120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8090292
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg