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N-Acetylaspartylglutamate (NAAG) Pretreatment Reduces Hypoxic-Ischemic Brain Damage and Oxidative Stress in Neonatal Rats

N-acetylaspartylglutamate (NAAG), the most abundant peptide transmitter in the mammalian nervous system, activates mGluR3 at presynaptic sites, inhibiting the release of glutamate, and acts on mGluR3 on astrocytes, stimulating the release of neuroprotective growth factors (TGF-β). NAAG can also affe...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Main Authors: Bratek, Ewelina, Ziembowicz, Apolonia, Salinska, Elzbieta
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555246/
https://ncbi.nlm.nih.gov/pubmed/32957477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9090877
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