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N-Acetylaspartylglutamate (NAAG) Pretreatment Reduces Hypoxic-Ischemic Brain Damage and Oxidative Stress in Neonatal Rats

N-acetylaspartylglutamate (NAAG), the most abundant peptide transmitter in the mammalian nervous system, activates mGluR3 at presynaptic sites, inhibiting the release of glutamate, and acts on mGluR3 on astrocytes, stimulating the release of neuroprotective growth factors (TGF-β). NAAG can also affe...

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Bibliografiske detaljer
Udgivet i:Antioxidants (Basel)
Main Authors: Bratek, Ewelina, Ziembowicz, Apolonia, Salinska, Elzbieta
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555246/
https://ncbi.nlm.nih.gov/pubmed/32957477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9090877
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