Nephroprotective Effect of Cilastatin against Gentamicin-Induced Renal Injury In Vitro and In Vivo without Altering Its Bactericidal Efficiency

Gentamicin is a used antibiotic that causes nephrotoxicity in 10–20% of treatment periods, which limits its use considerably. Our results have shown that cilastatin may be a promising therapeutic alternative in toxin-induced acute kidney injury (AKI). Here, we investigated its potential use as a nep...

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Dettagli Bibliografici
Pubblicato in:Antioxidants (Basel)
Autori principali: Jado, Juan Carlos, Humanes, Blanca, González-Nicolás, María Ángeles, Camaño, Sonia, Lara, José Manuel, López, Beatriz, Cercenado, Emilia, García-Bordas, Julio, Tejedor, Alberto, Lázaro, Alberto
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555100/
https://ncbi.nlm.nih.gov/pubmed/32899204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9090821
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