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Protective Effects of Cilastatin against Vancomycin-Induced Nephrotoxicity
Vancomycin is a very effective antibiotic for treatment of severe infections. However, its use in clinical practice is limited by nephrotoxicity. Cilastatin is a dehydropeptidase I inhibitor that acts on the brush border membrane of the proximal tubule to prevent accumulation of imipenem and toxicit...
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| Publicado no: | Biomed Res Int |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4609390/ https://ncbi.nlm.nih.gov/pubmed/26504822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/704382 |
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