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Cisplatin-induced renal inflammation is ameliorated by cilastatin nephroprotection
BACKGROUND: Cisplatin is a potent chemotherapeutic drug whose nephrotoxic effect is a major complication and a dose-limiting factor for antitumoral therapy. There is much evidence that inflammation contributes to the pathogenesis of cisplatin-induced nephrotoxicity. We found that cilastatin, a renal...
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| Publicado no: | Nephrol Dial Transplant |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6251639/ https://ncbi.nlm.nih.gov/pubmed/28340076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfx005 |
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