Anti-Inflammatory Activity of Kurarinone Involves Induction of HO-1 via the KEAP1/Nrf2 Pathway

Kurarinone, a flavonoid isolated from the roots of Sophora flavescens, was suggested to exert potent antioxidant and immunosuppressive effects. However, the underlying mechanisms remain unclear. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a key transcription factor that regulates the antio...

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Bibliografske podrobnosti
izdano v:Antioxidants (Basel)
Main Authors: Nishikawa, Sakiko, Inoue, Yasumichi, Hori, Yuka, Miyajima, Chiharu, Morishita, Daisuke, Ohoka, Nobumichi, Hida, Shigeaki, Makino, Toshiaki, Hayashi, Hidetoshi
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554885/
https://ncbi.nlm.nih.gov/pubmed/32916869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9090842
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