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Agonist Binding and G Protein Coupling in Histamine H(2) Receptor: A Molecular Dynamics Study

The histamine H [Formula: see text] receptor (H(2)R) plays an important role in the regulation of gastric acid secretion. Therefore, it is a main drug target for the treatment of gastroesophageal reflux or peptic ulcer disease. However, there is as of yet no 3D-structural information available hampe...

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Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Conrad, Marcus, Söldner, Christian A., Miao, Yinglong, Sticht, Heinrich
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554837/
https://ncbi.nlm.nih.gov/pubmed/32932742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186693
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