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Agonist Binding and G Protein Coupling in Histamine H(2) Receptor: A Molecular Dynamics Study
The histamine H [Formula: see text] receptor (H(2)R) plays an important role in the regulation of gastric acid secretion. Therefore, it is a main drug target for the treatment of gastroesophageal reflux or peptic ulcer disease. However, there is as of yet no 3D-structural information available hampe...
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| Veröffentlicht in: | Int J Mol Sci |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7554837/ https://ncbi.nlm.nih.gov/pubmed/32932742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186693 |
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