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Both Amyloid-β Peptide and Tau Protein Are Affected by an Anti-Amyloid-β Antibody Fragment in Elderly 3xTg-AD Mice

Alzheimer’s disease (AD) is the most common dementia worldwide. According to the amyloid hypothesis, the early accumulation of the Aβ-peptide triggers tau phosphorylation, synaptic dysfunction, and eventually neuronal death leading to cognitive impairment, as well as behavioral and psychological sym...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Roda, Alejandro R., Montoliu-Gaya, Laia, Serra-Mir, Gabriel, Villegas, Sandra
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554787/
https://ncbi.nlm.nih.gov/pubmed/32927795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186630
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