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Sulforaphane Inhibits MGO-AGE-Mediated Neuroinflammation by Suppressing NF-κB, MAPK, and AGE–RAGE Signaling Pathways in Microglial Cells

Advanced glycation end products (AGEs) are produced through the binding of glycated protein or lipid with sugar, and they are known to be involved in the pathogenesis of both age-dependent and independent neurological complications. Among dicarbonyl compounds, methylglyoxal (MGO), which is produced...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antioxidants (Basel)
Prif Awduron: Subedi, Lalita, Lee, Jae Hyuk, Gaire, Bhakta Prasad, Kim, Sun Yeou
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554773/
https://ncbi.nlm.nih.gov/pubmed/32859007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9090792
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