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Sulforaphane Inhibits MGO-AGE-Mediated Neuroinflammation by Suppressing NF-κB, MAPK, and AGE–RAGE Signaling Pathways in Microglial Cells

Advanced glycation end products (AGEs) are produced through the binding of glycated protein or lipid with sugar, and they are known to be involved in the pathogenesis of both age-dependent and independent neurological complications. Among dicarbonyl compounds, methylglyoxal (MGO), which is produced...

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Publicado en:Antioxidants (Basel)
Main Authors: Subedi, Lalita, Lee, Jae Hyuk, Gaire, Bhakta Prasad, Kim, Sun Yeou
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554773/
https://ncbi.nlm.nih.gov/pubmed/32859007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9090792
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