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Anti-Inflammatory Effect of Sulforaphane on LPS-Activated Microglia Potentially through JNK/AP-1/NF-κB Inhibition and Nrf2/HO-1 Activation

Sulforaphane (SFN), a potent nuclear factor erythroid 2-related factor 2 (Nrf2) activator, is present in the species of the Brassicaceae, especially in broccoli sprouts. In this study, the effects of SFN against microglial activation and inflammation, and the potential mechanisms involved, were anal...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Subedi, Lalita, Lee, Jae Hyuk, Yumnam, Silvia, Ji, Eunhee, Kim, Sun Yeou
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6406309/
https://ncbi.nlm.nih.gov/pubmed/30813369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8020194
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