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Mitochondrial Targeted Therapy with Elamipretide (MTP-131) as an Adjunct to Tumor Necrosis Factor Inhibition for Traumatic Optic Neuropathy in the Acute Setting

Traumatic optic neuropathy (TON) can occur following blunt trauma to the orbit and can lead to permanent vision loss. In this study, we investigated the effectiveness of elamipretide (MTP-131), a small mitochondrially-targeted tetrapeptide, in conjunction with etanercept, a tumor necrosis factor (TN...

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Dettagli Bibliografici
Pubblicato in:Exp Eye Res
Autori principali: Tse, Brian C., Dvoriantchikova, Galina, Tao, Wensi, Gallo, Ryan A., Lee, John Y., Ivanov, Dmitry, Tse, David T., Pelaez, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554259/
https://ncbi.nlm.nih.gov/pubmed/32758490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2020.108178
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