Mitochondrial Targeted Therapy with Elamipretide (MTP-131) as an Adjunct to Tumor Necrosis Factor Inhibition for Traumatic Optic Neuropathy in the Acute Setting

Traumatic optic neuropathy (TON) can occur following blunt trauma to the orbit and can lead to permanent vision loss. In this study, we investigated the effectiveness of elamipretide (MTP-131), a small mitochondrially-targeted tetrapeptide, in conjunction with etanercept, a tumor necrosis factor (TN...

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Publicado en:Exp Eye Res
Autores principales: Tse, Brian C., Dvoriantchikova, Galina, Tao, Wensi, Gallo, Ryan A., Lee, John Y., Ivanov, Dmitry, Tse, David T., Pelaez, Daniel
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554259/
https://ncbi.nlm.nih.gov/pubmed/32758490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2020.108178
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