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Mitochondrial Targeted Therapy with Elamipretide (MTP-131) as an Adjunct to Tumor Necrosis Factor Inhibition for Traumatic Optic Neuropathy in the Acute Setting

Traumatic optic neuropathy (TON) can occur following blunt trauma to the orbit and can lead to permanent vision loss. In this study, we investigated the effectiveness of elamipretide (MTP-131), a small mitochondrially-targeted tetrapeptide, in conjunction with etanercept, a tumor necrosis factor (TN...

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Bibliografske podrobnosti
izdano v:Exp Eye Res
Main Authors: Tse, Brian C., Dvoriantchikova, Galina, Tao, Wensi, Gallo, Ryan A., Lee, John Y., Ivanov, Dmitry, Tse, David T., Pelaez, Daniel
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554259/
https://ncbi.nlm.nih.gov/pubmed/32758490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2020.108178
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