Wnt/β-catenin signaling regulates adipose tissue lipogenesis and adipocyte-specific loss is rigorously defended by neighboring stromal-vascular cells

OBJECTIVE: Canonical Wnt/β-catenin signaling is a well-studied endogenous regulator of mesenchymal cell fate determination, promoting osteoblastogenesis and inhibiting adipogenesis. However, emerging genetic evidence in humans links a number of Wnt pathway members to body fat distribution, obesity,...

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Bibliografiske detaljer
Udgivet i:Mol Metab
Main Authors: Bagchi, Devika P., Nishii, Akira, Li, Ziru, DelProposto, Jennifer B., Corsa, Callie A., Mori, Hiroyuki, Hardij, Julie, Learman, Brian S., Lumeng, Carey N., MacDougald, Ormond A.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554252/
https://ncbi.nlm.nih.gov/pubmed/32919095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.101078
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