Wntless regulates lipogenic gene expression in adipocytes and protects against diet-induced metabolic dysfunction

OBJECTIVE: Obesity is a key risk factor for many secondary chronic illnesses, including type 2 diabetes and cardiovascular disease. Canonical Wnt/β-catenin signaling is established as an important endogenous inhibitor of adipogenesis. This pathway is operative in mature adipocytes; however, its role...

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Pubblicato in:Mol Metab
Autori principali: Bagchi, Devika P., Li, Ziru, Corsa, Callie A., Hardij, Julie, Mori, Hiroyuki, Learman, Brian S., Lewis, Kenneth T., Schill, Rebecca L., Romanelli, Steven M., MacDougald, Ormond A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264081/
https://ncbi.nlm.nih.gov/pubmed/32325263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.100992
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