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Wntless regulates lipogenic gene expression in adipocytes and protects against diet-induced metabolic dysfunction
Objective: Obesity is a key risk factor for many secondary chronic illnesses, including type 2 diabetes and cardiovascular disease. Canonical Wnt/β-catenin signaling is established as an important endogenous inhibitor of adipogenesis. This pathway is operative in mature adipocytes; however, its role...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2020-09-01
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Colecção: | Molecular Metabolism |
Assuntos: | |
Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2212877820300661 |
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