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Wntless regulates lipogenic gene expression in adipocytes and protects against diet-induced metabolic dysfunction

Objective: Obesity is a key risk factor for many secondary chronic illnesses, including type 2 diabetes and cardiovascular disease. Canonical Wnt/β-catenin signaling is established as an important endogenous inhibitor of adipogenesis. This pathway is operative in mature adipocytes; however, its role...

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Main Authors: Devika P. Bagchi, Ziru Li, Callie A. Corsa, Julie Hardij, Hiroyuki Mori, Brian S. Learman, Kenneth T. Lewis, Rebecca L. Schill, Steven M. Romanelli, Ormond A. MacDougald
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020-09-01
Colecção:Molecular Metabolism
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Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2212877820300661
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