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Outer Membranes of Polymyxin-Resistant Acinetobacter baumannii with Phosphoethanolamine-modified Lipid A and Lipopolysaccharide Loss Display Different Atomic-Scale Interactions with Polymyxins

Resistance to the last-line polymyxins is increasingly reported in multidrug-resistant Gram-negative pathogens, including Acinetobacter baumannii which develops resistance via either lipid A modification or even lipopolysaccharides (LPS) loss in the outer membrane (OM). Considering these two differe...

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Bibliografiske detaljer
Udgivet i:ACS Infect Dis
Main Authors: Jiang, Xukai, Yang, Kai, Han, Mei-Ling, Yuan, Bing, Li, Jingliang, Gong, Bin, Velkov, Tony, Schreiber, Falk, Wang, Lushan, Li, Jian
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554230/
https://ncbi.nlm.nih.gov/pubmed/32871077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.0c00330
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