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Gfi1 upregulates c-Myc expression and promotes c-Myc-driven cell proliferation
Gfi1 is a zinc-finger transcriptional repressor that plays an important role in hematopoiesis. When aberrantly activated, Gfi1 may function as a weak oncoprotein in the lymphoid system, but collaborates strongly with c-Myc in lymphomagenesis. The mechanism by which Gfi1 collaborates with c-Myc in ly...
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| Publicado en: | Sci Rep |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7554040/ https://ncbi.nlm.nih.gov/pubmed/33051558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74278-4 |
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