Active immunoprophylaxis with a synthetic DNA-encoded monoclonal anti-respiratory syncytial virus scFv-Fc fusion protein confers protection against infection and durable activity

Respiratory Syncytial virus (RSV) is a major threat to many vulnerable populations. There are currently no approved vaccines, and RSV remains a high unmet global medical need. Here we describe the employment of a novel synthetic DNA-encoded antibody technology platform to develop and deliver an engi...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Schultheis, Katherine, Pugh, Holly M, Oh, Janet, Nguyen, Jacklyn, Yung, Bryan, Reed, Charles, Cooch, Neil, Chen, Jing, Yan, Jian, Muthumani, Kar, Humeau, Laurent M., Weiner, David B., Broderick, Kate E., Smith, Trevor R. F.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7553682/
https://ncbi.nlm.nih.gov/pubmed/32544376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2020.1748979
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