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Active immunoprophylaxis with a synthetic DNA-encoded monoclonal anti-respiratory syncytial virus scFv-Fc fusion protein confers protection against infection and durable activity

Respiratory Syncytial virus (RSV) is a major threat to many vulnerable populations. There are currently no approved vaccines, and RSV remains a high unmet global medical need. Here we describe the employment of a novel synthetic DNA-encoded antibody technology platform to develop and deliver an engi...

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Vydáno v:Hum Vaccin Immunother
Hlavní autoři: Schultheis, Katherine, Pugh, Holly M, Oh, Janet, Nguyen, Jacklyn, Yung, Bryan, Reed, Charles, Cooch, Neil, Chen, Jing, Yan, Jian, Muthumani, Kar, Humeau, Laurent M., Weiner, David B., Broderick, Kate E., Smith, Trevor R. F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7553682/
https://ncbi.nlm.nih.gov/pubmed/32544376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2020.1748979
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