Active immunoprophylaxis with a synthetic DNA-encoded monoclonal anti-respiratory syncytial virus scFv-Fc fusion protein confers protection against infection and durable activity

Respiratory Syncytial virus (RSV) is a major threat to many vulnerable populations. There are currently no approved vaccines, and RSV remains a high unmet global medical need. Here we describe the employment of a novel synthetic DNA-encoded antibody technology platform to develop and deliver an engi...

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Dettagli Bibliografici
Pubblicato in:Hum Vaccin Immunother
Autori principali: Schultheis, Katherine, Pugh, Holly M, Oh, Janet, Nguyen, Jacklyn, Yung, Bryan, Reed, Charles, Cooch, Neil, Chen, Jing, Yan, Jian, Muthumani, Kar, Humeau, Laurent M., Weiner, David B., Broderick, Kate E., Smith, Trevor R. F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2020
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7553682/
https://ncbi.nlm.nih.gov/pubmed/32544376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2020.1748979
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