Pharmacokinetics and Biodistribution of Thymoquinone-loaded Nanostructured Lipid Carrier After Oral and Intravenous Administration into Rats

BACKGROUND: Thymoquinone (TQ), an active compound isolated from Nigella sativa, has been proven to exhibit various biological properties such as antioxidant. Although oral delivery of TQ is valuable, it is limited by poor oral bioavailability and low solubility. Recently, TQ-loaded nanostructured li...

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Detaylı Bibliyografya
Yayımlandı:Int J Nanomedicine
Asıl Yazarlar: Zakarial Ansar, Fatin Hannani, Latifah, Saiful Yazan, Wan Kamal, Wan Hamirul Bahrin, Khong, Khei Choong, Ng, Yen, Foong, Jia Ning, Gopalsamy, Banulata, Ng, Wei Keat, How, Chee Wun, Ong, Yong Sze, Abdullah, Rasedee, Aziz, Mohd Yusmaidie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Dove 2020
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7553255/
https://ncbi.nlm.nih.gov/pubmed/33116496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S262395
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