Pharmacokinetics and Biodistribution of Thymoquinone-loaded Nanostructured Lipid Carrier After Oral and Intravenous Administration into Rats

BACKGROUND: Thymoquinone (TQ), an active compound isolated from Nigella sativa, has been proven to exhibit various biological properties such as antioxidant. Although oral delivery of TQ is valuable, it is limited by poor oral bioavailability and low solubility. Recently, TQ-loaded nanostructured li...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Int J Nanomedicine
Main Authors: Zakarial Ansar, Fatin Hannani, Latifah, Saiful Yazan, Wan Kamal, Wan Hamirul Bahrin, Khong, Khei Choong, Ng, Yen, Foong, Jia Ning, Gopalsamy, Banulata, Ng, Wei Keat, How, Chee Wun, Ong, Yong Sze, Abdullah, Rasedee, Aziz, Mohd Yusmaidie
פורמט: Artigo
שפה:Inglês
יצא לאור: Dove 2020
נושאים:
Original Research
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7553255/
https://ncbi.nlm.nih.gov/pubmed/33116496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S262395
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