Pharmacokinetics and Biodistribution of Thymoquinone-loaded Nanostructured Lipid Carrier After Oral and Intravenous Administration into Rats

BACKGROUND: Thymoquinone (TQ), an active compound isolated from Nigella sativa, has been proven to exhibit various biological properties such as antioxidant. Although oral delivery of TQ is valuable, it is limited by poor oral bioavailability and low solubility. Recently, TQ-loaded nanostructured li...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Zakarial Ansar, Fatin Hannani, Latifah, Saiful Yazan, Wan Kamal, Wan Hamirul Bahrin, Khong, Khei Choong, Ng, Yen, Foong, Jia Ning, Gopalsamy, Banulata, Ng, Wei Keat, How, Chee Wun, Ong, Yong Sze, Abdullah, Rasedee, Aziz, Mohd Yusmaidie
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7553255/
https://ncbi.nlm.nih.gov/pubmed/33116496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S262395
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