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SARS-CoV-2-specific peripheral T follicular helper cells correlate with neutralizing antibodies and increase during convalescence.

T-cell immunity is likely to play a role in protection against SARS-CoV-2 by helping generate neutralizing antibodies. We longitudinally studied CD4 T-cell responses to the M, N, and S structural proteins of SARS-CoV-2 in 21 convalescent individuals. Within the first two months following symptom ons...

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Detalhes bibliográficos
Publicado no:medRxiv
Main Authors: Boppana, Sushma, Qin, Kai, Files, Jacob K, Russell, Ronnie M., Stoltz, Regina, Bibollet-Ruche, Frederic, Bansal, Anju, Erdmann, Nathan, Hahn, Beatrice H., Goepfert, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7553179/
https://ncbi.nlm.nih.gov/pubmed/33052359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.10.07.20208488
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