Population pharmacokinetics of lopinavir/ritonavir in Covid-19 patients

OBJECTIVE: To develop a population pharmacokinetic model for lopinavir boosted by ritonavir in coronavirus disease 2019 (Covid-19) patients. METHODS: Concentrations of lopinavir/ritonavir were assayed by an accredited LC-MS/MS method. The population pharmacokinetics of lopinavir was described using...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Eur J Clin Pharmacol
Päätekijät: Alvarez, Jean Claude, Moine, Pierre, Davido, Benjamin, Etting, Isabelle, Annane, Djillali, Larabi, Islam Amine, Simon, Nicolas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer Berlin Heidelberg 2020
Aiheet:
Pharmacokinetics and Disposition
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7552959/
https://ncbi.nlm.nih.gov/pubmed/33048175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-020-03020-w
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