Targeting aberrant expression of Notch-1 in ALDH(+) cancer stem cells in breast cancer

We have previously reported that high aldehyde dehydrogenase (ALDH) enzyme activity in breast cancer cells results in breast cancer stem cell (BCSC) properties by upregualting Notch-1 and epithelial mesenchymal markers. This results in chemoresistance in breast cancer. Here, we examined the function...

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Detalhes bibliográficos
Publicado no:Mol Carcinog
Main Authors: Pal, Deeksha, Kolluru, Venkatesh, Chandrasekaran, Balaji, Baby, Becca V, Aman, Masarath, Suman, Suman, Sirimulla, Suman, Sanders, Mary Ann, Alatassi, Houda, Ankem, Murali K, Damodaran, Chendil
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7552110/
https://ncbi.nlm.nih.gov/pubmed/27753148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22579
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