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Targeting Notch Signaling in Colorectal Cancer
The activation of Notch signaling is implicated in tumorigenesis in the colon due to the induction of pro-survival signaling in colonic epithelial cells. Chemoresistance is a major obstacle for treatment and for the complete eradication of colorectal cancer (CRC), hence, the inhibition of Notch is a...
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| Publicado no: | Curr Colorectal Cancer Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4226438/ https://ncbi.nlm.nih.gov/pubmed/25395896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11888-014-0252-3 |
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