Targeting aberrant expression of Notch-1 in ALDH(+) cancer stem cells in breast cancer

We have previously reported that high aldehyde dehydrogenase (ALDH) enzyme activity in breast cancer cells results in breast cancer stem cell (BCSC) properties by upregualting Notch-1 and epithelial mesenchymal markers. This results in chemoresistance in breast cancer. Here, we examined the function...

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Publicat a:Mol Carcinog
Autors principals: Pal, Deeksha, Kolluru, Venkatesh, Chandrasekaran, Balaji, Baby, Becca V, Aman, Masarath, Suman, Suman, Sirimulla, Suman, Sanders, Mary Ann, Alatassi, Houda, Ankem, Murali K, Damodaran, Chendil
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7552110/
https://ncbi.nlm.nih.gov/pubmed/27753148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22579
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