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Development of Ligand-Drug Conjugates Targeting Melanoma through the Overexpressed Melanocortin 1 Receptor

[Image: see text] Melanoma is a lethal form of skin cancer. Despite recent breakthroughs of BRAF-V600E and PD-1 inhibitors showing remarkable clinical responses, melanoma can eventually survive these targeted therapies and become resistant. To solve the drug resistance issue, we designed and synthes...

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Vydáno v:ACS Pharmacol Transl Sci
Hlavní autoři: Zhou, Yang, Mowlazadeh Haghighi, Saghar, Liu, Zekun, Wang, Lingzhi, Hruby, Victor J., Cai, Minying
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2020
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7551717/
https://ncbi.nlm.nih.gov/pubmed/33073191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00072
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