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Development of melanoma-targeted polymer micelles by conjugation of a Melanocortin 1 Receptor (MC1R) specific ligand

The incidence of malignant melanoma is rising faster than that of any other cancer in the United States. Due to its high expression on the surface of melanomas, MC1R has been investigated as a target for selective imaging and therapeutic agents against melanoma. Eight ligands were screened against c...

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Detalhes bibliográficos
Main Authors: Barkey, Natalie M., Tafreshi, Narges K., Josan, Jatinder S., De Silva, Channa R., Sill, Kevin N., Hruby, Victor J., Gillies, Robert J., Morse, David L., Vagner, Josef
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302579/
https://ncbi.nlm.nih.gov/pubmed/22011200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm201226w
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