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Novel Polymeric Hybrid Nanocarrier for Curcumin and Survivin shRNA Co-delivery Augments Tumor Penetration and Promotes Synergistic Tumor Suppression

A major barrier for co-delivery of gene medicine with small molecular chemotherapeutic drugs in solid tumors is the inadequate tumor penetration and transfection. In this study, a novel polymeric nanocarrier with integrated properties of tumor penetration, nuclear targeting, and pH-responsive featur...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Front Chem
Κύριοι συγγραφείς: Xu, Bei, Zhou, Wen, Cheng, Lizhi, Zhou, Yang, Fang, Aiping, Jin, Chaohui, Zeng, Jun, Song, Xiangrong, Guo, Xia
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Frontiers Media S.A. 2020
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550741/
https://ncbi.nlm.nih.gov/pubmed/33134256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2020.00762
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