Plasmid-based Survivin shRNA and GRIM-19 carried by attenuated Salmonella suppresses tumor cell growth

Persistent activation of Survivin and its overexpression contribute to the formation, progression and metastasis of several different tumor types. Therefore, Survivin is an ideal target for RNA interference mediated-growth inhibition. Blockade of Survivin using specific short hairpin RNAs (shRNA) ca...

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Bibliografiske detaljer
Main Authors: Liu, Yan-Bo, Zhang, Ling, Guo, Ya-Xiong, Gao, Li-Fang, Liu, Xi-Chun, Zhao, Li-Juan, Guo, Bao-Feng, Zhao, Li-Jing, Zhao, Xue-Jian, Xu, De-Qi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720080/
https://ncbi.nlm.nih.gov/pubmed/22580637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aja.2011.179
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