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Attenuated Salmonella typhimurium carrying shRNA-expressing vectors elicit RNA interference in murine bladder tumors

AIM: To examine whether attenuated Salmonella typhimurium (S typhimurium) could be used as an anti-cancer agent or a tumor-targeting vehicle for delivering shRNA-expressing pDNA into cancer cells in a mouse tumor model. METHODS: Mouse bladder transitional cancer cell line (BTT-T739) expressing GFP w...

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Détails bibliographiques
Auteurs principaux: Yang, Nan, Li, Sheng-hua, Lü, Yun-zhe, Chen, Li-shan, Ren, Da-ming
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002778/
https://ncbi.nlm.nih.gov/pubmed/21372828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.224
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