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The conserved AAA-ATPase PCH-2 (TRIP13) regulates spindle checkpoint strength
Spindle checkpoint strength is dictated by the number of unattached kinetochores, cell volume, and cell fate. We show that the conserved AAA-ATPase PCH-2/TRIP13, which remodels the checkpoint effector Mad2 from an active conformation to an inactive one, controls checkpoint strength in Caenorhabditis...
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| 發表在: | Mol Biol Cell |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The American Society for Cell Biology
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7550697/ https://ncbi.nlm.nih.gov/pubmed/32697629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-05-0310 |
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