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Improved Single-Cell Proteome Coverage Using Narrow-Bore Packed NanoLC Columns and Ultrasensitive Mass Spectrometry

Single-cell proteomics can provide unique insights into biological processes by resolving heterogeneity that is obscured by bulk measurements. Gains in the overall sensitivity and proteome coverage through improvements in sample processing and analysis increase the information content obtained from...

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Bibliografske podrobnosti
izdano v:Anal Chem
Main Authors: Cong, Yongzheng, Liang, Yiran, Motamedchaboki, Khatereh, Huguet, Romain, Truong, Thy, Zhao, Rui, Shen, Yufeng, Lopez-Ferrer, Daniel, Zhu, Ying, Kelly, Ryan T.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550239/
https://ncbi.nlm.nih.gov/pubmed/31913019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b04631
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