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Improved Single-Cell Proteome Coverage Using Narrow-Bore Packed NanoLC Columns and Ultrasensitive Mass Spectrometry

Single-cell proteomics can provide unique insights into biological processes by resolving heterogeneity that is obscured by bulk measurements. Gains in the overall sensitivity and proteome coverage through improvements in sample processing and analysis increase the information content obtained from...

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Dades bibliogràfiques
Publicat a:Anal Chem
Autors principals: Cong, Yongzheng, Liang, Yiran, Motamedchaboki, Khatereh, Huguet, Romain, Truong, Thy, Zhao, Rui, Shen, Yufeng, Lopez-Ferrer, Daniel, Zhu, Ying, Kelly, Ryan T.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550239/
https://ncbi.nlm.nih.gov/pubmed/31913019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b04631
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