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lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements
Massively parallel reporter assays (MPRAs) can simultaneously measure the function of thousands of candidate regulatory sequences (CRSs) in a quantitative manner. In this method, CRSs are cloned upstream of a minimal promoter and reporter gene, alongside a unique barcode, and introduced into cells....
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| 出版年: | Nat Protoc |
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| 主要な著者: | , , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7550205/ https://ncbi.nlm.nih.gov/pubmed/32641802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-020-0333-5 |
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