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An enhanced molecular tension sensor based on bioluminescence resonance energy transfer (BRET)

Molecular tension sensors measure piconewton forces experienced by individual proteins in the context of the cellular microenvironment. Current genetically-encoded tension sensors use FRET to report on extension of a deformable peptide encoded in a cellular protein of interest. Here we present the d...

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Bibliographic Details
Published in:ACS Sens
Main Authors: Aird, Eric J., Tompkins, Kassidy J., Ramirez, Maria Paz, Gordon, Wendy R.
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550199/
https://ncbi.nlm.nih.gov/pubmed/31872754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssensors.9b00796
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