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Development and characterization of protein kinase B/AKT isoform-specific nanobodies
The serine/threonine protein kinase AKT is frequently over-activated in cancer and is associated with poor prognosis. As a central node in the PI3K/AKT/mTOR pathway, which regulates various processes considered to be hallmarks of cancer, this kinase has become a prime target for cancer therapy. Howe...
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| Udgivet i: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7549812/ https://ncbi.nlm.nih.gov/pubmed/33045011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240554 |
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