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VCA nanobodies target N-WASp to reduce invadopodium formation and functioning
Invasive cancer cells develop small actin-based protrusions called invadopodia, which perform a primordial role in metastasis and extracellular matrix remodelling. Neural Wiskott-Aldrich syndrome protein (N-WASp) is a scaffold protein which can directly bind to actin monomers and Arp2/3 and is a cru...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5609757/ https://ncbi.nlm.nih.gov/pubmed/28938008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185076 |
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