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A new survivin tracer tracks, delocalizes and captures endogenous survivin at different subcellular locations and in distinct organelles

Survivin, the smallest member of the inhibitor of apoptosis protein family, plays a central role during mitosis and exerts a cytoprotective function. Survivin is highly expressed in most cancer types and contributes to multiple facets of carcinogenesis. The molecular mechanisms underlying its highly...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Beghein, Els, Van Audenhove, Isabel, Zwaenepoel, Olivier, Verhelle, Adriaan, De Ganck, Ariane, Gettemans, Jan
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981888/
https://ncbi.nlm.nih.gov/pubmed/27514728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31177
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