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RAS ubiquitylation modulates effector interactions

RAS proteins function as molecular switches that regulate cellular growth by cycling between active GTP- and inactive GDP bound states. While RAS activity is modulated by factors (guanine nucleotide exchange and GTPase activating proteins) that control levels of active Ras-GTP, RAS proteins also und...

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Detalhes bibliográficos
Publicado no:Small GTPases
Main Authors: Thurman, Ryan, Siraliev-Perez, Edhriz, Campbell, Sharon L.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549706/
https://ncbi.nlm.nih.gov/pubmed/29185849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2017.1371267
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