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Genetic deletion of the Rho GEF Net1 impairs mouse macrophage motility and actin cytoskeletal organization

Macrophages are innate immune cells that constantly patrol an organism to fulfill protective and homeostatic roles. Previous studies have shown that Rho GTPase activity is required for macrophage mobility, yet the roles of upstream regulatory proteins controlling Rho GTPase function in these cells a...

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Detalhes bibliográficos
Publicado no:Small GTPases
Main Authors: Zuo, Yan, d'Aigle, John, Chauhan, Anjali, Frost, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549643/
https://ncbi.nlm.nih.gov/pubmed/29173011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2017.1405772
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