Discovery of a Cyclic Choline Analog That Inhibits Anaerobic Choline Metabolism by Human Gut Bacteria

[Image: see text] The anaerobic conversion of choline to trimethylamine (TMA) by the human gut microbiota has been linked to multiple human diseases. The potential impact of this microbial metabolic activity on host health has inspired multiple efforts to identify small molecule inhibitors. Here, we...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:ACS Med Chem Lett
Main Authors: Bollenbach, Maud, Ortega, Manuel, Orman, Marina, Drennan, Catherine L., Balskus, Emily P.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2020
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549264/
https://ncbi.nlm.nih.gov/pubmed/33062182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00005
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki